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MoschenHTS/README.md

Henrique Tamanini Silva Moschen

Ph.D. student in Animal Biology at the University of Brasília (UnB), based in the Toxinology Laboratory, Center for Molecular Biotechnology.

Available for freelance biostatistics, data science, and bioinformatics work, for hospitals, laboratories, and research groups, in Brasília and remotely.

Education

  • Ph.D. in Animal Biology, University of Brasília (UnB) — in progress
  • M.Sc. in Molecular Biology, University of Brasília (UnB)
  • B.Sc. in Biological Sciences, Federal University of Espírito Santo (UFES)

Research areas

Toxinology and bioprospecting, applied to venom peptide characterization and the rational design of bioinspired peptides for medical and biotechnological applications. Work covers venom peptide isolation and sequence analysis, protein structural modeling, membrane molecular dynamics, ion channel electrophysiology, and regulatory zebrafish embryo toxicity testing under OECD guidelines. Also involved in environmental metagenomics for bioremediation, as a member of the Environmental Metagenomics and Biotechnology Research Group (Prof. Ricardo Henrique Kruger, University of Brasília).

Publications

  • Prado-Lopes, N.; Fagundes, D.; et al.; Moschen, H.; et al.; de Bem, A.F. "Sex- and age-dependent mitochondrial dysfunction and cognitive impairment in a mouse model of familial hypercholesterolemia." Biology of Sex Differences, v.17, 109, 2026. 10.1186/s13293-026-00893-x
  • Ribeiro de Jesus, N.; et al.; Tamanini Silva Moschen, H.; et al.; Vicente, C.R. "Genomic and Epidemiological Characterization of DENV-1 and DENV-2 Co-Circulation During the 2023–2024 Dengue Epidemic in Espírito Santo, Brazil." Journal of Medical Virology, v.98, e71078, 2026. 10.1002/jmv.71078
  • Barcellos Madeira Rosa, Y.; Tamanini Silva Moschen, H.; et al. "Climate change impacts on dengue transmission areas in Espírito Santo state, Brazil." Oxford Open Immunology, v.5, 2024. 10.1093/oxfimm/iqae011 · PMC11398874

Software and data

  • ZebraFET — desktop application for the OECD TG 236 Fish Embryo Acute Toxicity test. Covers experimental design, plate layout, daily well scoring, LC50/NOEC/LOEC and sublethal endpoint analysis, OECD validity checks, and automated report generation. 10.5281/zenodo.20183712 · registered with Brazil's National Institute of Industrial Property (INPI BR512026001141-8)
  • catanduba-simoni-venom-peptides — sequence and structural-biology pipeline for Catanduba simoni Kv4 gating-modifier venom peptides. Covers BLAST/MSA, structural co-folding, and membrane molecular dynamics. 10.5281/zenodo.22139140

Links

Popular repositories Loading

  1. ZebraFET ZebraFET Public

    Open-source desktop application for OECD TG 236 zebrafish embryo toxicity (FET) assays — experimental design, daily well scoring, LC50/NOEC/LOEC and sublethal endpoint analysis, OECD validity check…

    Python 1

  2. catanduba-simoni-venom-peptides catanduba-simoni-venom-peptides Public

    Sequence and structural-biology pipeline (BLAST/MSA, Boltz-2 co-folding, membrane MD) for Catanduba simoni Kv4 gating-modifier toxins

    Python

  3. MoschenHTS MoschenHTS Public

    Profile README