diff --git a/Detectors/Upgrades/ITS3/CMakeLists.txt b/Detectors/Upgrades/ITS3/CMakeLists.txt
index bdaf1b4bf4292..a4c05db1d607e 100644
--- a/Detectors/Upgrades/ITS3/CMakeLists.txt
+++ b/Detectors/Upgrades/ITS3/CMakeLists.txt
@@ -13,9 +13,9 @@
 #add_link_options(-fsanitize=address)
 
 add_subdirectory(simulation)
-add_subdirectory(alignment)
+#add_subdirectory(alignment)
 add_subdirectory(base)
 add_subdirectory(workflow)
 add_subdirectory(reconstruction)
 add_subdirectory(macros)
-add_subdirectory(study)
+#add_subdirectory(study)
diff --git a/Detectors/Upgrades/ITS3/macros/CMakeLists.txt b/Detectors/Upgrades/ITS3/macros/CMakeLists.txt
index 0801c2cf9a099..a2c28510dee42 100644
--- a/Detectors/Upgrades/ITS3/macros/CMakeLists.txt
+++ b/Detectors/Upgrades/ITS3/macros/CMakeLists.txt
@@ -20,7 +20,7 @@ macro(its3_add_macro file)
       O2::ITSMFTSimulation
       O2::ITS3Reconstruction
       O2::ITS3Simulation
-      O2::ITS3Align
+#     O2::ITS3Align
       O2::MathUtils
       O2::SimulationDataFormat
       O2::DetectorsBase
@@ -31,4 +31,4 @@ endmacro()
 
 add_subdirectory(test)
 add_subdirectory(eve)
-add_subdirectory(align)
+#add_subdirectory(align)
diff --git a/cmake/O2RootMacroExclusionList.cmake b/cmake/O2RootMacroExclusionList.cmake
index 5fea628edd22f..a6e5ef5c73405 100644
--- a/cmake/O2RootMacroExclusionList.cmake
+++ b/cmake/O2RootMacroExclusionList.cmake
@@ -57,6 +57,12 @@ list(APPEND O2_ROOT_MACRO_EXCLUSION_LIST
             macro/putCondition.C
             macro/rootlogon.C
             macro/CreateSampleIRFrames.C
+            Detectors/Upgrades/ITS3/macros/align/CheckHitResiduals.C
+            Detectors/Upgrades/ITS3/macros/align/CheckResidualsITS3.C
+            Detectors/Upgrades/ITS3/study/macros/PlotMisalignment.C
+            Detectors/Upgrades/ITS3/study/macros/PlotPulls.C
+            Detectors/Upgrades/ITS3/study/macros/PlotResiduals.C
+            Detectors/Upgrades/ITS3/study/macros/PlotDCA.C
             Detectors/Upgrades/ALICE3/macros/ALICE3Field.C)
 
 if(NOT BUILD_SIMULATION)